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Pacc1em1Zzq
Endonuclease-mediated Allele Detail
Summary
Symbol: Pacc1em1Zzq
Name: proton activated chloride channel 1; endonuclease-mediated mutation 1, Zhaozhu Qiu
MGI ID: MGI:6356324
Synonyms: Pac floxed
Gene: Pacc1  Location: Chr1:191058109-191083111 bp, + strand  Genetic Position: Chr1, 96.28 cM
Alliance: Pacc1em1Zzq page
Mutation
origin
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Endonuclease-mediated (Conditional ready)
Mutation:    Insertion
 
Mutation detailsCRISPR/Cas9 mutagenesis was used to insert two loxP sites, one 397 bp upstream of exon 2 and a second 309 bp dpwnstream of exon 2. (J:273611)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pacc1 Mutation:  22 strains or lines available
References
Original:  J:273611 Yang J, et al., PAC, an evolutionarily conserved membrane protein, is a proton-activated chloride channel. Science. 2019 Apr 26;364(6438):395-399
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory