Gata6^{tm1(EGFP/cre/ERT2)Fmw}
Targeted Allele Detail

Summary

• Symbol: Gata6^{tm1(EGFP/cre/ERT2)Fmw}
• Name: GATA binding protein 6; targeted mutation 1, Fiona M Watt
• MGI ID: MGI:6358513
• Synonyms: Gata6EGFPCreERT2
• Gene: Gata6 Location: Chr18:11052510-11085636 bp, + strand Genetic Position: Chr18, 5.63 cM
• Alliance: Gata6^{tm1(EGFP/cre/ERT2)Fmw} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:246513
• Parent Cell Line: JM8 (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Gata6^{tm1(EGFP/cre/ERT2)Fmw} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Gata6 (MGI:107516)

• A EGFPCreERT2 expression element was targeted in-frame into the first non-coding exon of the gene. (J:246513)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Gata6 (mouse) Summary of all recombinase alleles driven by Gata6. Alliance mouse Gata6 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Gata6 Mutation: 35 strains or lines available

References

• Original: J:246513 Donati G, et al., Wounding induces dedifferentiation of epidermal Gata6+ cells and acquisition of stem cell properties. Nat Cell Biol. 2017 Jun;19(6):603-613
• All: 5 reference(s)