Egr2^tm2Ics
Targeted Allele Detail

Summary

• Symbol: Egr2^tm2Ics
• Name: early growth response 2; targeted mutation 2, Mouse Clinical Institute
• MGI ID: MGI:6361936
• Synonyms: Krox20^Cflox
• Gene: Egr2 Location: Chr10:67371305-67378018 bp, + strand Genetic Position: Chr10, 34.96 cM, cytoband B5
• Alliance: Egr2^tm2Ics page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:243865
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of element C. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of the element. (J:243865)

Expression

In Mice Carrying this Mutation:

7 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Egr2 Mutation: 33 strains or lines available

References

• Original: J:243865 Thierion E, et al., Krox20 hindbrain regulation incorporates multiple modes of cooperation between cis-acting elements. PLoS Genet. 2017 Jul;13(7):e1006903
• All: 1 reference(s)