Tprg1l^tm1.1Tdre
Targeted Allele Detail

Summary

• Symbol: Tprg1l^tm1.1Tdre
• Name: transformation related protein 63 regulated 1 like; targeted mutation 1.1, Thomas Dresbach
• MGI ID: MGI:6385131
• Synonyms: Mover^flox
• Gene: Tprg1l Location: Chr4:154241942-154245123 bp, - strand Genetic Position: Chr4, 83.88 cM, cytoband E2
• Alliance: Tprg1l^tm1.1Tdre page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:282820
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: The targeting vector is designed to insert a loxP site in exon 1 (upstream of the translation start site), and an FRT-flanked neo cassette followed by a second loxP site downstream of exon 3. Flp-mediated recombination removed the FRT-flanked neo cassette. (J:282820)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tprg1l Mutation: 16 strains or lines available

References

• Original: J:282820 Akula AK, et al., The Calmodulin Binding Region of the Synaptic Vesicle Protein Mover Is Required for Homomeric Interaction and Presynaptic Targeting. Front Mol Neurosci. 2019;12:249
• All: 1 reference(s)