Nudt21^tm1.2Ejwpj
Targeted Allele Detail

Summary

• Symbol: Nudt21^tm1.2Ejwpj
• Name: nudix hydrolase 21; targeted mutation 1.2, Eric Wagner
• MGI ID: MGI:6385511
• Gene: Nudt21 Location: Chr8:94746031-94763667 bp, - strand Genetic Position: Chr8, 46.05 cM
• Alliance: Nudt21^tm1.2Ejwpj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:283034
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exons 2 and 3 were floxed. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed exons 2 and 3. (J:283034)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nudt21 Mutation: 28 strains or lines available

References

• Original: J:283034 Weng T, et al., Downregulation of CFIm25 amplifies dermal fibrosis through alternative polyadenylation. J Exp Med. 2020 Feb 3;217(2)
• All: 2 reference(s)