Txndc17^tm1.2Ees
Targeted Allele Detail

Summary

• Symbol: Txndc17^tm1.2Ees
• Name: thioredoxin domain containing 17; targeted mutation 1.2, Edward E Schmidt
• MGI ID: MGI:6385646
• Synonyms: Txndc17^null
• Gene: Txndc17 Location: Chr11:72098373-72100841 bp, + strand Genetic Position: Chr11, 43.92 cM
• Alliance: Txndc17^tm1.2Ees page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:283042
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: (C57BL/6 x 129S6/SvEvTac)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: The targeting vector is designed to insert a loxP site upstream of exon 1 and an FRT-loxP-SV40 terminator cassette containing a self excising FRT-flanked ACN cassette inserted downstream of the 3' UTR. Cre-mediated recombination removed exons 1 thorugh 4. (J:283042)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Txndc17 Mutation: 10 strains or lines available

References

• Original: J:283042 Doka E, et al., Control of protein function through oxidation and reduction of persulfidated states. Sci Adv. 2020 Jan;6(1):eaax8358
• All: 1 reference(s)