Ikzf1^m1Anu
Chemically induced Allele Detail

Summary

• Symbol: Ikzf1^m1Anu
• Name: IKAROS family zinc finger 1; mutation 1, Australian National University
• MGI ID: MGI:6390950
• Synonyms: Ikzf1^L132P
• Gene: Ikzf1 Location: Chr11:11634980-11722926 bp, + strand Genetic Position: Chr11, 7.02 cM
• Alliance: Ikzf1^m1Anu page

Mutation origin

• Strain of Origin: C57BL/6NCrlAnu
• Project Collection: APF ENU Mutagenesis

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a T to C mutation at position 665 in exon 4 that results in the amino acid substitution leucine to proline at position 132. (J:303895)
• Inheritance: Recessive

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ikzf1 Mutation: 30 strains or lines available

References

• Original: J:303895 Boast B, et al., A Point Mutation in IKAROS ZF1 Causes a B Cell Deficiency in Mice. J Immunol. 2021 Apr 1;206(7):1505-1514
• All: 1 reference(s)