Ksr2^tm1.1Itl
Targeted Allele Detail

Summary

• Symbol: Ksr2^tm1.1Itl
• Name: kinase suppressor of ras 2; targeted mutation 1.1, inGenious Targeting Laboratory
• MGI ID: MGI:6393251
• Gene: Ksr2 Location: Chr5:117552067-117906061 bp, + strand Genetic Position: Chr5, 56.88 cM
• Alliance: Ksr2^tm1.1Itl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:262342
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: LoxP sites were inserted to flank exon 3. An frt-flanked selection cassette was removed via FLP-mediated recombination. (J:262342)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ksr2 Mutation: 42 strains or lines available

References

• Original: J:262342 Guo L, et al., Kinase Suppressor of Ras 2 (KSR2) expression in the brain regulates energy balance and glucose homeostasis. Mol Metab. 2017 Feb;6(2):194-205
• All: 2 reference(s)