Slc6a4^tm1Jy
Targeted Allele Detail

Summary

• Symbol: Slc6a4^tm1Jy
• Name: solute carrier family 6 (neurotransmitter transporter, serotonin), member 4; targeted mutation 1, Jiying Sze
• MGI ID: MGI:6393418
• Synonyms: SERT^fl
• Gene: Slc6a4 Location: Chr11:76889429-76923166 bp, + strand Genetic Position: Chr11, 46.18 cM
• Alliance: Slc6a4^tm1Jy page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:222808
• Parent Cell Line: PTL1 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6J)F1

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exons 3 and 4 floxed. (J:222808)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Slc6a4 Mutation: 56 strains or lines available

References

• Original: J:222808 Chen X, et al., Disruption of Transient Serotonin Accumulation by Non-Serotonin-Producing Neurons Impairs Cortical Map Development. Cell Rep. 2015 Jan 14
• All: 5 reference(s)