Ace2^em1Qhs
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ace2^em1Qhs
• Name: angiotensin converting enzyme 2; endonuclease-mediated mutation 1, Qian-Hui Shang
• MGI ID: MGI:6415670
• Gene: Ace2 Location: ChrX:162922338-162971414 bp, + strand Genetic Position: ChrX, 76.12 cM, cytoband F5
• Alliance: Ace2^em1Qhs page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 genome editing technology was used to generate a deletion of exons 3-18 of the gene. (J:285491)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ace2 Mutation: 66 strains or lines available

References

• Original: J:285491 Liu C, et al., [Establishment of Ace2 knockout mouse model with CRISPR/Cas9 gene targeting technology]. Sheng Li Xue Bao. 2019 Aug 25;71(4):588-596
• All: 2 reference(s)