Tg(Camk2a-PLA2G4A)9Mrl
Transgene Detail
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Symbol: |
Tg(Camk2a-PLA2G4A)9Mrl |
Name: |
transgene insertion 9, Merck Research Laboratory |
MGI ID: |
MGI:6434522 |
Transgene: |
Tg(Camk2a-PLA2G4A)9Mrl Location: unknown
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Alliance: |
Tg(Camk2a-PLA2G4A)9Mrl page
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Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(Camk2a-PLA2G4A)9Mrl expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
human |
PLA2G4A (5321) |
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Mutation details: The transgenic construct contains 5 the 8.5 kb mouse CaM-kinase II alpha chain (mCamk2a) promoter fragment, an 850 bp DNA fragment containing the human beta-globin intron 2, and 2247bp ORF of human PLA2G4A cDNA (GenBank Acc# NM_024420), followed by 221bp of SV40 poly A sequence at the 3 end in a pGL3 vector backbone (Promega). A consensus KOZAK sequence was added upstream of the starter ATG. Line 9 has the medium expression level of the transgene in the brain.
(J:147112)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:147112 Taconic, Information obtained from Taconic website. MGI Direct Data Submission. 2006-2017; |
All: |
1 reference(s) |
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