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Tg(Camk2a-PLA2G4A)9Mrl
Transgene Detail
Summary
Symbol: Tg(Camk2a-PLA2G4A)9Mrl
Name: transgene insertion 9, Merck Research Laboratory
MGI ID: MGI:6434522
Transgene: Tg(Camk2a-PLA2G4A)9Mrl  Location: unknown  
Alliance: Tg(Camk2a-PLA2G4A)9Mrl page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Camk2a-PLA2G4A)9Mrl expresses 1 gene
 
Mutation detailsThe transgenic construct contains 5 the 8.5 kb mouse CaM-kinase II alpha chain (mCamk2a) promoter fragment, an 850 bp DNA fragment containing the human beta-globin intron 2, and 2247bp ORF of human PLA2G4A cDNA (GenBank Acc# NM_024420), followed by 221bp of SV40 poly A sequence at the 3 end in a pGL3 vector backbone (Promega). A consensus KOZAK sequence was added upstream of the starter ATG. Line 9 has the medium expression level of the transgene in the brain. (J:147112)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:147112 Taconic, Information obtained from Taconic website. MGI Direct Data Submission. 2006-2017;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory