Tmem79^tm1.1Pfal
Targeted Allele Detail

Summary

• Symbol: Tmem79^tm1.1Pfal
• Name: transmembrane protein 79; targeted mutation 1.1, Padraic Fallon
• MGI ID: MGI:6441169
• Synonyms: Tmem79^fl
• Gene: Tmem79 Location: Chr3:88236351-88241761 bp, - strand Genetic Position: Chr3, 38.8 cM, cytoband F1
• Alliance: Tmem79^tm1.1Pfal page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:290038
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exon 2 was floxed. Flp-mediated recombination remvoed the FRT-flanked neomycin resistance cassette inserted into intron 2. (J:290038)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tmem79 Mutation: 23 strains or lines available

References

• Original: J:290038 Saunders SP, et al., Dysregulated skin barrier function in Tmem79 mutant mice promotes IL-17A-dependent spontaneous skin and lung inflammation. Allergy. 2020 Jul 9
• All: 1 reference(s)