Chrnd^em1H
Endonuclease-mediated Allele Detail

Summary

• Symbol: Chrnd^em1H
• Name: cholinergic receptor, nicotinic, delta polypeptide; endonuclease-mediated mutation 1, Harwell
• MGI ID: MGI:6450521
• Synonyms: CHRND-R399H-EM1-B6
• Gene: Chrnd Location: Chr1:87118329-87127792 bp, + strand Genetic Position: Chr1, 44.07 cM
• Alliance: Chrnd^em1H page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Single point mutation
• Mutation details: CRISPR-targeting introduced the amino acid substitution of arginine with histidine at position 399 (R399H). (J:90559)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Chrnd Mutation: 32 strains or lines available

References

• Original: J:90559 The Mammalian Genetics Unit at Harwell, Information obtained from the Mammalian Genetics Unit, Medical Research Council (MRC), Harwell, UK. Unpublished. 2004-2013
• All: 1 reference(s)