Kcnc1^em2H
Endonuclease-mediated Allele Detail

Summary

• Symbol: Kcnc1^em2H
• Name: potassium voltage gated channel, Shaw-related subfamily, member 1; endonuclease-mediated mutation 1, Harwell
• MGI ID: MGI:6451585
• Synonyms: KCNC1-E380C-EM2-B6
• Gene: Kcnc1 Location: Chr7:46045921-46088128 bp, + strand Genetic Position: Chr7, 30.1 cM
• Alliance: Kcnc1^em2H page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Nucleotide substitutions
• Mutation details: CRISPR-targeting introduced the amino acid substitution of a glutamic acid with a cysteine at position 380 (E380C). (J:90559)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Kcnc1 Mutation: 41 strains or lines available

References

• Original: J:90559 The Mammalian Genetics Unit at Harwell, Information obtained from the Mammalian Genetics Unit, Medical Research Council (MRC), Harwell, UK. Unpublished. 2004-2013
• All: 1 reference(s)