Pde2a^em3H
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pde2a^em3H
• Name: phosphodiesterase 2A, cGMP-stimulated; endonuclease-mediated mutation 3, Harwell
• MGI ID: MGI:6451729
• Synonyms: PDE2A-D479G-EM3-B6N
• Gene: Pde2a Location: Chr7:101070905-101162026 bp, + strand Genetic Position: Chr7, 54.57 cM
• Alliance: Pde2a^em3H page

Mutation origin

• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Nucleotide substitutions
• Mutation details: CRISPR-targeting introduced the amino acid substitution of aspartic acid with glycine at position 479 (D479G). (J:90559)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pde2a Mutation: 58 strains or lines available

References

• Original: J:90559 The Mammalian Genetics Unit at Harwell, Information obtained from the Mammalian Genetics Unit, Medical Research Council (MRC), Harwell, UK. Unpublished. 2004-2013
• All: 1 reference(s)