Pkhd1^em2H
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pkhd1^em2H
• Name: polycystic kidney and hepatic disease 1; endonuclease-mediated mutation 2, Harwell
• MGI ID: MGI:6451731
• Synonyms: PKHD1-T37M-EM2-C3H
• Gene: Pkhd1 Location: Chr1:20128003-20688288 bp, - strand Genetic Position: Chr1, 6.27 cM, cytoband A2-A5
• Alliance: Pkhd1^em2H page

Mutation origin

• Strain of Origin: C3H/HeH

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Single point mutation
• Mutation details: CRISPR-targeting introduced the amino acid substitution of threonine with methionine at position 37 (T37M). (J:90559)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Pkhd1 Mutation: 225 strains or lines available

References

• Original: J:90559 The Mammalian Genetics Unit at Harwell, Information obtained from the Mammalian Genetics Unit, Medical Research Council (MRC), Harwell, UK. Unpublished. 2004-2013
• All: 1 reference(s)