Rbpj^em2H
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rbpj^em2H
• Name: recombination signal binding protein for immunoglobulin kappa J region; endonuclease-mediated mutation 2, Harwell
• MGI ID: MGI:6451740
• Synonyms: RBPJ-T223R-EM2-B6N
• Gene: Rbpj Location: Chr5:53713121-53814787 bp, + strand Genetic Position: Chr5, 29.37 cM, cytoband C1-C3
• Alliance: Rbpj^em2H page

Mutation origin

• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Nucleotide substitutions
• Mutation details: CRISPR-targeting introduced the amino acid substitution of threonine with arginine at position 223 (T223R). (J:90559)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Rbpj Mutation: 193 strains or lines available

References

• Original: J:90559 The Mammalian Genetics Unit at Harwell, Information obtained from the Mammalian Genetics Unit, Medical Research Council (MRC), Harwell, UK. Unpublished. 2004-2013
• All: 1 reference(s)