Gnai2^em1Btar
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gnai2^em1Btar
• Name: G protein subunit alpha i2; endonuclease-mediated mutation 1, Basile Tarchini
• MGI ID: MGI:6466534
• Synonyms: Galphai2^KO, Gnai2^em1Tmos
• Gene: Gnai2 Location: Chr9:107491324-107512542 bp, - strand Genetic Position: Chr9, 58.43 cM
• Alliance: Gnai2^em1Btar page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 genome editing technology was used to generate a deletion of exons 2-4. (J:274644)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gnai2 Mutation: 56 strains or lines available

References

• Original: J:274644 Jean P, et al., Intrinsic planar polarity mechanisms influence the position-dependent regulation of synapse properties in inner hair cells. Proc Natl Acad Sci U S A. 2019 Apr 30;116(18):9084-9093
• All: 2 reference(s)