Ppara^tm1.2Ics
Targeted Allele Detail

Summary

• Symbol: Ppara^tm1.2Ics
• Name: peroxisome proliferator activated receptor alpha; targeted mutation 1.2, Mouse Clinical Institute
• MGI ID: MGI:6468265
• Gene: Ppara Location: Chr15:85619184-85687020 bp, + strand Genetic Position: Chr15, 40.42 cM
• Alliance: Ppara^tm1.2Ics page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:82809
• Parent Cell Line: P1 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 4. An FRT-flanked neomycin resistance cassette was inserted downstream of exon 4. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed exon 4. (J:82809)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ppara Mutation: 42 strains or lines available

References

• Original: J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013
• All: 1 reference(s)