Gpr88^tm2.1Ics
Targeted Allele Detail

Summary

• Symbol: Gpr88^tm2.1Ics
• Name: G-protein coupled receptor 88; targeted mutation 2.1, Mouse Clinical Institute
• MGI ID: MGI:6469456
• Synonyms: Gpr88^Venus
• Gene: Gpr88 Location: Chr3:116043304-116047123 bp, - strand Genetic Position: Chr3, 50.23 cM, cytoband G1
• Alliance: Gpr88^tm2.1Ics page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:296332
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: The targeting vector is designed to insert a Venus yellow fluorescent protein cDNA into exon 2 and to replace the endogenous STOP codon with a 5aa linker. An FRT-flanked neomycin resistance (neo) cassette was placed downstream. Transient flp-mediated recombination removed the floxed neo cassette. (J:296332)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gpr88 Mutation: 16 strains or lines available

References

• Original: J:296332 Ehrlich AT, et al., Mapping GPR88-Venus illuminates a novel role for GPR88 in sensory processing. Brain Struct Funct. 2018 Apr;223(3):1275-1296
• All: 1 reference(s)