Klhl18^lowf
Spontaneous Allele Detail

Summary

• Symbol: Klhl18^lowf
• Name: kelch-like 18; low frequency
• MGI ID: MGI:6470867
• Gene: Klhl18 Location: Chr9:110254994-110305762 bp, - strand Genetic Position: Chr9, 59.92 cM
• Alliance: Klhl18^lowf page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Spontaneous (Not Specified)
• Mutation: Single point mutation
• Mutation details: A spontaneous mutation resulted in the amino acid substitution C to A (g.9:110455454C>A; p.Val55Phe; GRCm38). (J:311444)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Klhl18 Mutation: 36 strains or lines available

References

• Original: J:311444 Ingham NJ, et al., Inner hair cell dysfunction in Klhl18 mutant mice leads to low frequency progressive hearing loss. PLoS One. 2021;16(10):e0258158
• All: 2 reference(s)