Ffar4^tm1.2Vpoi
Targeted Allele Detail

Summary

• Symbol: Ffar4^tm1.2Vpoi
• Name: free fatty acid receptor 4; targeted mutation 1.2, Vincent Poitout
• MGI ID: MGI:6477328
• Synonyms: Gpr120^delta
• Gene: Ffar4 Location: Chr19:38085527-38102711 bp, + strand Genetic Position: Chr19, 32.73 cM
• Alliance: Ffar4^tm1.2Vpoi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:297264
• Parent Cell Line: iTL IC1 (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The alleles contains a floxed exon 1 and FRT-flanked neomycin resistance cassette. Flp-mediated recombination removed the selection cassette. The promoter and exon 1 were deleted following cre-mediated recombination. (J:297264)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ffar4 Mutation: 25 strains or lines available

References

• Original: J:297264 Croze ML, et al., Free-fatty acid receptor 4 inhibitory signaling in delta cells regulates islet hormone secretion in mice. Mol Metab. 2021;45
• All: 2 reference(s)