Epxtm2.1(HBEGF)Jlee
Targeted Allele Detail
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Symbol: |
Epxtm2.1(HBEGF)Jlee |
Name: |
eosinophil peroxidase; targeted mutation 2.1, James Lee |
MGI ID: |
MGI:6489574 |
Synonyms: |
EPXtm1.1(DTR)JLee, iPHIL-epx |
Gene: |
Epx Location: Chr11:87754826-87766362 bp, - strand Genetic Position: Chr11, 52.25 cM
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Alliance: |
Epxtm2.1(HBEGF)Jlee page
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Germline Transmission: |
Earliest citation of germline transmission:
J:266723
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
C57BL/6
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Allele Type: |
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Targeted (Inserted expressed sequence) |
Mutation: |
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Insertion
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Epxtm2.1(HBEGF)Jlee expresses
1 gene
Knock-in expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
human |
HBEGF (1839) |
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Mutation details: The knock-in allele contains a human Diptheria Toxin receptor (HBEGF) driven by the endogenous promoter and followed by an IRES sequence then the endogenous coding sequence. Cre-recombination removed the floxed neomycin selection cassette.
(J:266723)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Epx Mutation: |
33 strains or lines available
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Original: |
J:266723 Jacobsen EA, et al., Eosinophil activities modulate the immune/inflammatory character of allergic respiratory responses in mice. Allergy. 2014 Mar;69(3):315-27 |
All: |
3 reference(s) |
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