Iap5-1^solo
Allele Detail

Summary

• Symbol: Iap5-1^solo
• Name: intracisternal A-type particle, Pgm2 linked; solo
• MGI ID: MGI:6510295
• Synonyms: C57iap1^solo
• Gene: Iap5-1 Location: unknown Genetic Position: Chr5, Syntenic
• Alliance: Iap5-1^solo page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Not Applicable (Modified regulatory region)
• Mutation: Viral insertion
• Mutation details: This variant contains only the long terminal repeats (LTR) from the intracisternal A-particle retrovirus. Unlike the Iap5-1^full variant, the solo variant lacks a KRAB zinc finger protein binding site and is no longer subject to DNA methylation and H3K9 trimethylation. (J:302835)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Iap5-1 Mutation: 4 strains or lines available

References

• Original: J:302835 Bertozzi TM, et al., A spontaneous genetically-induced epiallele at a retrotransposon shapes host genome function. Elife. 2021;10:e65233
• All: 1 reference(s)