Gpsm2^tm2.1Fuma
Targeted Allele Detail

Summary

• Symbol: Gpsm2^tm2.1Fuma
• Name: G-protein signalling modulator 2 (AGS3-like, C. elegans); targeted mutation 2.1, Fumio Matsuzaki
• MGI ID: MGI:6695731
• Synonyms: LGN-null
• Gene: Gpsm2 Location: Chr3:108585954-108629625 bp, - strand Genetic Position: Chr3, 47.53 cM, cytoband F3
• Alliance: Gpsm2^tm2.1Fuma page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:304603
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exons 315 of the gene, encoding amino acids 19679 (the C-terminus) was deleted after recombination of flanking loxP sites. (J:304603)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gpsm2 Mutation: 26 strains or lines available

References

• Original: J:304603 Fujita I, et al., Endfoot regeneration restricts radial glial state and prevents translocation into the outer subventricular zone in early mammalian brain development. Nat Cell Biol. 2020 Jan;22(1):26-37
• All: 1 reference(s)