Tg(CAG-PPP5C)#Wey
Transgene Detail

Summary

• Symbol: Tg(CAG-PPP5C)#Wey
• Name: transgene insertion, Weidong Yong
• MGI ID: MGI:6716324
• Synonyms: Tg-hPP5
• Transgene: Tg(CAG-PPP5C)#Wey Location: unknown
• Alliance: Tg(CAG-PPP5C)#Wey page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(CAG-PPP5C)#Wey expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  PPP5C (5536)

  Ppp5c

  (MGI:102666)

  human cDNA

• Mutation details: This transgene insert comprises the following elements: the CAG promoter, the human protein phosphatase 5 catalytic subunit cDNA and beta-globin poly(A) signal sequence. (J:306076)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:306076 Dou L, et al., Over-expression of human PP5 gene in mice induces corneal hyperplasia and leads to ocular surface squamous neoplasia. Biochem Biophys Res Commun. 2020 Aug 20;529(2):487-493
• All: 1 reference(s)