Npr1^em1Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Npr1^em1Smoc
• Name: natriuretic peptide receptor 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:6719490
• Synonyms: NprA^flox
• Gene: Npr1 Location: Chr3:90357898-90373173 bp, - strand Genetic Position: Chr3, 39.23 cM
• Alliance: Npr1^em1Smoc page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting floxed exon 2. (J:307074)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Npr1 Mutation: 60 strains or lines available

References

• Original: J:307074 Chen B, et al., Cardiacspecific deletion of natriuretic peptide receptor A induces differential myocardial expression of circular RNA and mRNA molecules involved in metabolism in mice. Mol Med Rep. 2021 Jan;23(1)
• All: 1 reference(s)