Myh11^{Tg(CMV-fad2)#aGkmn}
Transgenic Allele Detail

Summary

• Symbol: Myh11^{Tg(CMV-fad2)#aGkmn}
• Name: myosin, heavy polypeptide 11, smooth muscle; transgene insertion #a, Kemian Gou
• MGI ID: MGI:6783434
• Gene: Myh11 Location: Chr16:14012392-14109227 bp, - strand Genetic Position: Chr16, 9.71 cM
• Alliance: Myh11^{Tg(CMV-fad2)#aGkmn} page

Transgene origin

• Strain of Origin: (C57BL/6J x DBA/2J)F2

Transgene description

• Transgene Type: Transgenic (Null/knockout)
• Mutation: Insertion
• Mutation details: The CMV promoter drives ubiquitous expression of cotton (Gossypium hirsutum) omega-6 fatty acid desaturase-2 (fad2). Ten lines were generated. Unnamed line #a inserted into intron 22. Western blot analysis confirmed the absence of protein expression at E15.5 and E195 in the bladder and stomach. (J:288571, J:309353)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Myh11 Mutation: 93 strains or lines available

References

• Original: J:288571 Chen Q, et al., Generation of fad2 transgenic mice that produce omega-6 fatty acids. Sci China C Life Sci. 2009 Nov;52(11):1048-54
• All: 2 reference(s)