Del(5Rr45-Lmbr1)1Dje
Targeted Allele Detail

Summary

• Symbol: Del(5Rr45-Lmbr1)1Dje
• Name: deletion, Chr5, Douglas J Epstein 1
• MGI ID: MGI:6836767
• Synonyms: Del(C1-Z), Shh^deltaSBE5
• Gene: Del(5Rr45-Lmbr1)1Dje Location: unknown Genetic Position: Chr5, Syntenic

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Targeted (Modified regulatory region, Null/knockout)
• Mutations: Insertion, Intergenic deletion, Intragenic deletion
• Del(5Rr45-Lmbr1)1Dje involves 6 genes/genome features (Rr46, Rr29, Rr45 ...) View all
• Mutation details: Genomic sequence chr5:29,413,90129,642,246 (build GRCm37 mm9), which includes Ssh brain enhancer SBE5 and Shh enhancers MFCS4, MACS1 and MFCS1 (ZRS) and the Rnf32 gene and 3' part of the Lmbr1 gene, was deleted through cre-mediated recombination between loxP sites in Sleeping Beauty transposon sensor alleles ShhSB1 and Z2D. (J:231964)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(5Rr45-Lmbr1)1Dje Mutation: 0 strains or lines available

References

• Original: J:231964 Yao Y, et al., Cis-regulatory architecture of a brain signaling center predates the origin of chordates. Nat Genet. 2016 May;48(5):575-80
• All: 1 reference(s)