Rdx^em2Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rdx^em2Gpt
• Name: radixin; endonuclease-mediated mutation 2, GemPharmatech Co., Ltd
• MGI ID: MGI:6856634
• Synonyms: Rdx^loxP
• Gene: Rdx Location: Chr9:51958450-52000038 bp, + strand Genetic Position: Chr9, 28.62 cM
• Alliance: Rdx^em2Gpt page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Exons 4 and 5 were flanked by loxP sites using CRISPR/Cas9 technology. (J:317592)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rdx Mutation: 47 strains or lines available

References

• Original: J:317592 Zhang Y, et al., Oocyte-derived microvilli control female fertility by optimizing ovarian follicle selection in mice. Nat Commun. 2021 May 5;12(1):2523
• All: 1 reference(s)