Mettl5^em1Zph
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mettl5^em1Zph
• Name: methyltransferase 5, N6-adenosine; endonuclease-mediated mutation 1, Zhan-Peng Huang
• MGI ID: MGI:7256503
• Synonyms: METTL5^fl
• Gene: Mettl5 Location: Chr2:69701542-69715959 bp, - strand Genetic Position: Chr2, 40.95 cM, cytoband C3
• Alliance: Mettl5^em1Zph page

Mutation origin

• Strain of Origin: J:321970

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting floxed exons 2 through 4. (J:321970)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mettl5 Mutation: 40 strains or lines available

References

• Original: J:321970 Han Y, et al., Loss of m(6)A Methyltransferase METTL5 Promotes Cardiac Hypertrophy Through Epitranscriptomic Control of SUZ12 Expression. Front Cardiovasc Med. 2022;9:852775
• All: 1 reference(s)