Sftpctm2.1(NtTA)Thbr
Targeted Allele Detail
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Symbol: |
Sftpctm2.1(NtTA)Thbr |
Name: |
surfactant associated protein C; targeted mutation 2.1, Thomas Braun |
MGI ID: |
MGI:7263085 |
Synonyms: |
SPC-2A-YFP-2A-tTA-N |
Gene: |
Sftpc Location: Chr14:70758389-70761521 bp, - strand Genetic Position: Chr14, 36.32 cM
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Alliance: |
Sftpctm2.1(NtTA)Thbr page
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Allele Type: |
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Targeted (Epitope tag, Reporter, Transactivator) |
Mutation: |
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Insertion
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Mutation details: Mice were generated by inserting a 2A sequence, YFP, 2A sequence, and the N-terminal fragment of tTA (aa 1-205) fused to the N terminal 102 amino acids of the DnaE split intein sequence from Nostoc punctiforme (Npu), FLAG tag, and Frt-flanked neomycin resistance cassette immediately in front of the stop codon of Sftpc coding sequence by homologous recombination. The Frt-flanked neomycin resistance cassette was removed by crossing with hACTB-Flpe deleter mice.
(J:323339)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Sftpc Mutation: |
23 strains or lines available
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Original: |
J:323339 Salwig I, et al., Bronchioalveolar stem cells are a main source for regeneration of distal lung epithelia in vivo. EMBO J. 2019 Jun 17;38(12):e102099 |
All: |
1 reference(s) |
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