Gstk1^em1Sunl
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gstk1^em1Sunl
• Name: glutathione S-transferase kappa 1; endonuclease-mediated mutation 1, Lin Sun
• MGI ID: MGI:7276226
• Synonyms: DsbA-L^-
• Gene: Gstk1 Location: Chr6:42222869-42227375 bp, + strand Genetic Position: Chr6, 20.52 cM
• Alliance: Gstk1^em1Sunl page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology generated a 68 bp deletion in exon 3. (J:294243)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gstk1 Mutation: 16 strains or lines available

References

• Original: J:294243 Chen X, et al., Disulfide-bond A oxidoreductase-like protein protects against ectopic fat deposition and lipid-related kidney damage in diabetic nephropathy. Kidney Int. 2019 Apr;95(4):880-895
• All: 3 reference(s)