Tg(CAG-ACE2,-luc)1Smoc
Transgene Detail

Summary

• Symbol: Tg(CAG-ACE2,-luc)1Smoc
• Name: transgene insertion 1, Shanghai Model Organisms Center
• MGI ID: MGI:7279190
• Synonyms: CAG-hACE2-IRES-Luc-Tg
• Transgene: Tg(CAG-ACE2,-luc)1Smoc Location: unknown
• Alliance: Tg(CAG-ACE2,-luc)1Smoc page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Tg(CAG-ACE2,-luc)1Smoc expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  ACE2 (59272)

  Ace2	(MGI:1917258)

• The CAG promoter drives expression of a human ACE2-IRES-Luciferase-WPRE-polyA cassette. (J:238766)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:324335 Li C, et al., Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody. Cell. 2022 Apr 14;185(8):1389-1401.e18
• All: 5 reference(s)