Drd2^em1Cirf
Endonuclease-mediated Allele Detail

Summary

• Symbol: Drd2^em1Cirf
• Name: dopamine receptor D2; endonuclease-mediated mutation 1, Francisco Ciruela
• MGI ID: MGI:7284184
• Gene: Drd2 Location: Chr9:49251927-49319477 bp, + strand Genetic Position: Chr9, 26.72 cM
• Alliance: Drd2^em1Cirf page

Mutation origin

• Strain of Origin: CD-1

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/cas9 mediated recombination created an 8 nt deletion (AATGGGTC) in exon 2. (J:325042)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Drd2 Mutation: 70 strains or lines available

References

• Original: J:325042 Taura J, et al., Behavioral control by striatal adenosine A2A -dopamine D2 receptor heteromers. Genes Brain Behav. 2018 Apr;17(4):e12432
• All: 1 reference(s)