Hdac10^tm1Tac
Targeted Allele Detail

Summary

• Symbol: Hdac10^tm1Tac
• Name: histone deacetylase 10; targeted mutation 1.1, Taconic
• MGI ID: MGI:7311611
• Gene: Hdac10 Location: Chr15:89007510-89012903 bp, - strand Genetic Position: Chr15, 44.64 cM
• Alliance: Hdac10^tm1Tac page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:296294
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neomycin selection cassette replaced exons 1-16. (J:147112)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hdac10 Mutation: 37 strains or lines available

References

• Original: J:296294 Li Y, et al., HDAC10 Regulates Cancer Stem-Like Cell Properties in KRAS-Driven Lung Adenocarcinoma. Cancer Res. 2020 Aug 15;80(16):3265-3278
• All: 2 reference(s)