Gt(ROSA)26Sor^{tm2(EGFP/ZFP36L1)Tnr}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm2(EGFP/ZFP36L1)Tnr}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Martin Turner
• MGI ID: MGI:7325471
• Synonyms: GFPZFP36L1, Gt(Rosa)26Sor^{tm1(GFPZfp36l1)Tnr}
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm2(EGFP/ZFP36L1)Tnr} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:232475
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm2(EGFP/ZFP36L1)Tnr} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  ZFP36L1 (677)

  Zfp36l1

  (MGI:107946)

• Mutation details: The targeting construct inserted into the locus the human gene with an N-terminal fusion with the EGFP reporter gene. (J:232475)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 958 strains or lines available

References

• Original: J:232475 Galloway A, et al., RNA-binding proteins ZFP36L1 and ZFP36L2 promote cell quiescence. Science. 2016 Apr 22;352(6284):453-9
• All: 3 reference(s)