Terb1em1Hirok
Endonuclease-mediated Allele Detail
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Symbol: |
Terb1em1Hirok |
Name: |
telomere repeat binding bouquet formation protein 1; endonuclease-mediated mutation 1, Hiroki Shibuya |
MGI ID: |
MGI:7327606 |
Synonyms: |
Terb1deltaMYB |
Gene: |
Terb1 Location: Chr8:105173351-105236542 bp, - strand Genetic Position: Chr8, 53.04 cM
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Alliance: |
Terb1em1Hirok page
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Strain of Origin: |
Not Applicable
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Allele Type: |
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Endonuclease-mediated (Not Applicable) |
Mutation: |
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Single point mutation
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Mutation details: CRISPR-targeting introduced the mutation responsible for the introduction of a stop codon instead of glycine at position 704 (G704*) resulting in a premature termination before the MYB-like DNA-binding (MYB) domain.
(J:324793)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Terb1 Mutation: |
47 strains or lines available
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Original: |
J:324793 Zhang K, et al., The TERB1 MYB domain suppresses telomere erosion in meiotic prophase I. Cell Rep. 2022 Jan 25;38(4):110289 |
All: |
1 reference(s) |
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