Tg(TcrbDO11.10)#Dlo
Transgene Detail

Summary

• Symbol: Tg(TcrbDO11.10)#Dlo
• Name: transgene insertion, Dennis Y Loh
• MGI ID: MGI:7388207
• Transgene: Tg(TcrbDO11.10)#Dlo Location: unknown Genetic Position: Chr18, Syntenic
• Alliance: Tg(TcrbDO11.10)#Dlo page

Transgene origin

• Strain of Origin: (C57BL/6 x C3H)F1 x BALB/c

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The transgene contains a rearranged Tcrb gene and is expressed in the majority of T cells. The rearranged transgene encodes a chicken ovalbumin-specific MHC class II (I-A^d)-restricted T cell receptor beta chain. (J:70572)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:70572 Murphy KM, et al., Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo. Science. 1990 Dec 21;250(4988):1720-3
• All: 5 reference(s)