Plxnd1^tm1.2Tmj
Targeted Allele Detail

Summary

• Symbol: Plxnd1^tm1.2Tmj
• Name: plexin D1; targeted mutation 1.2, Thomas M Jessell
• MGI ID: MGI:7388559
• Gene: Plxnd1 Location: Chr6:115931772-115971966 bp, - strand Genetic Position: Chr6, 53.72 cM
• Alliance: Plxnd1^tm1.2Tmj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:330969
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: An frt flanked neo cassette with a loxP site was inserted upstream of exon 1 and an additional loxP site was inserted downstream of exon 1. Flp-mediated recombination removed the neo cassette and cre-mediated recombination removed exon 1. (J:330969)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Plxnd1 Mutation: 86 strains or lines available

References

• Original: J:330969 Martins LF, et al., Motor neurons use push-pull signals to direct vascular remodeling critical for their connectivity. Neuron. 2022 Oct 7
• All: 1 reference(s)