Reg3g^tm1Welj
Targeted Allele Detail

Summary

• Symbol: Reg3g^tm1Welj
• Name: regenerating islet-derived 3 gamma; targeted mutation 1, Jerry M Wells
• MGI ID: MGI:7398105
• Gene: Reg3g Location: Chr6:78443252-78445855 bp, - strand Genetic Position: Chr6, 34.78 cM, cytoband C
• Alliance: Reg3g^tm1Welj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:331545
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready, Reporter)
• Mutation: Insertion
• Mutation details: A construct containing a loxP site, splice acceptor, mouse Reg3g cDNA, FRT site, pgk-neo cassette, polyA sequence, splice donor, FRT site, loxP site, splice acceptor, and eGFP replaced exon 2 via homologous recombination. (J:331545)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Reg3g Mutation: 5 strains or lines available

References

• Original: J:331545 Loonen LM, et al., REG3gamma-deficient mice have altered mucus distribution and increased mucosal inflammatory responses to the microbiota and enteric pathogens in the ileum. Mucosal Immunol. 2014 Jul;7(4):939-47
• All: 1 reference(s)