Rr231598em1Smun
Endonuclease-mediated Allele Detail
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Symbol: |
Rr231598em1Smun |
Name: |
regulatory region 231598; endonuclease-mediated mutation 1, Stefan Mundlos |
MGI ID: |
MGI:7407309 |
Synonyms: |
deltaC2 |
Gene: |
Rr231598 Location: Chr11:111795001-111796000 bp, . strand Genetic Position: Chr11, Syntenic
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Alliance: |
Rr231598em1Smun page
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Strain of Origin: |
Not Specified
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Allele Type: |
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Endonuclease-mediated (Modified regulatory region) |
Mutation: |
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Intergenic deletion
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Mutation details: The CTCF-binding site in the Sox9 topologically associated domain (TAD) was targeted with an sgRNA (targeting TGTAAGTGGGCATTGCCACC) using CRISPR/Cas9 technology, resulting in its deletion.
(J:282642)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Rr231598 Mutation: |
0 strains or lines available
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Original: |
J:282642 Despang A, et al., Functional dissection of the Sox9-Kcnj2 locus identifies nonessential and instructive roles of TAD architecture. Nat Genet. 2019 Aug;51(8):1263-1271 |
All: |
1 reference(s) |
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