Yif1b^em1Hawu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Yif1b^em1Hawu
• Name: Yip1 interacting factor homolog B (S. cerevisiae); endonuclease-mediated mutation 1, Haibo Wu
• MGI ID: MGI:7408565
• Gene: Yif1b Location: Chr7:28937754-28947022 bp, + strand Genetic Position: Chr7, 16.94 cM, cytoband A3
• Alliance: Yif1b^em1Hawu page

Mutation origin

• Strain of Origin: B6.Cg-Tg(K18-ACE2)2Prlmn/J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology deleted exons 3-5 in Tg(K18-ACE2)1Prlmn expressing zygotes. (J:315744)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Yif1b Mutation: 23 strains or lines available

References

• Original: J:315744 Lin X, et al., Unconventional secretion of unglycosylated ORF8 is critical for the cytokine storm during SARS-CoV-2 infection. bioRxiv. 2021 Dec
• All: 1 reference(s)