Ddx3x^tm1.1Sdru
Targeted Allele Detail

Summary

• Symbol: Ddx3x^tm1.1Sdru
• Name: DEAD box helicase 3, X-linked; targeted mutation 1.1, Silvia De Rubeis
• MGI ID: MGI:7425293
• Synonyms: Ddx3x^flox
• Gene: Ddx3x Location: ChrX:13147261-13160222 bp, + strand Genetic Position: ChrX, 8.17 cM
• Alliance: Ddx3x^tm1.1Sdru page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:322019
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site and an FRT-flanked selection cassette was inserted upstream of exon 2 and a second loxP site downstream of exon 2. The selection cassette was removed via flp-mediated recombination leaving exon 2 floxed. (J:322019)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ddx3x Mutation: 10 strains or lines available

References

• Original: J:322019 Boitnott A, et al., Developmental and Behavioral Phenotypes in a Mouse Model of DDX3X Syndrome. Biol Psychiatry. 2021 Jun 7
• All: 1 reference(s)