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Ambra1tm1d(EUCOMM)Wtsi
Targeted Allele Detail
Summary
Symbol: Ambra1tm1d(EUCOMM)Wtsi
Name: autophagy/beclin 1 regulator 1; targeted mutation 1d, Wellcome Trust Sanger Institute
MGI ID: MGI:7448482
Gene: Ambra1  Location: Chr2:91560479-91749194 bp, + strand  Genetic Position: Chr2, 50.63 cM
Alliance: Ambra1tm1d(EUCOMM)Wtsi page
IMPC: Ambra1 gene page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:330579
Parent Cell Line:  JM8A3.N1 (ES Cell)
Strain of Origin:  C57BL/6N-Atm1Brd
Project Collection: EUCOMM
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ambra1 Mutation:  118 strains or lines available
References
Original:  J:330579 Gambarotto L, et al., Ambra1 deficiency impairs mitophagy in skeletal muscle. J Cachexia Sarcopenia Muscle. 2022 Aug;13(4):2211-2224
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory