Tg(CD2-TNF/HBB)211Gkl
Transgene Detail

Summary

• Symbol: Tg(CD2-TNF/HBB)211Gkl
• Name: transgene insertion 211, George Kollias
• MGI ID: MGI:7451300
• Transgene: Tg(CD2-TNF/HBB)211Gkl Location: unknown
• Alliance: Tg(CD2-TNF/HBB)211Gkl page

Transgene origin

• Strain of Origin: (CBA x C57BL/6)

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The transgene contains a T cell-specific human CD2 gene locus control region (LCR) driving expression of wild-type human gene with a membrane-associated protein. Lines 211 and 233 were generated. (J:278669)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:278669 Probert L, et al., Wasting, ischemia, and lymphoid abnormalities in mice expressing T cell-targeted human tumor necrosis factor transgenes. J Immunol. 1993 Aug 15;151(4):1894-906
• All: 1 reference(s)