Cdc20^em1Bcgen
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cdc20^em1Bcgen
• Name: cell division cycle 20; endonuclease-mediated mutation 1, Biocytogen LLC
• MGI ID: MGI:7461084
• Synonyms: Cdc20^f
• Gene: Cdc20 Location: Chr4:118290098-118294540 bp, - strand Genetic Position: Chr4, 54.61 cM
• Alliance: Cdc20^em1Bcgen page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Using CRISPR/Cas9 technology, two loxP sites flanking the exon1-7 of mouse Cdc20 gene were inserted. (J:314351)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cdc20 Mutation: 30 strains or lines available

References

• Original: J:314351 Du Y, et al., CDC20 promotes bone formation via APC/C dependent ubiquitination and degradation of p65. EMBO Rep. 2021 Sep 6;22(9):e52576
• All: 1 reference(s)