Ddx3x^tm1Pngr
Targeted Allele Detail

Summary

• Symbol: Ddx3x^tm1Pngr
• Name: DEAD box helicase 3, X-linked; targeted mutation 1, Josef M Penninger
• MGI ID: MGI:7482466
• Synonyms: Ddx3x^fl
• Gene: Ddx3x Location: ChrX:13147261-13160222 bp, + strand Genetic Position: ChrX, 8.17 cM
• Alliance: Ddx3x^tm1Pngr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:291333
• Parent Cell Line: A9 (ES Cell)
• Strain of Origin: (C57BL/6 x 129P2/OlaHsd)F1

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• The targeting construct floxed exon 2. (J:291333)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ddx3x Mutation: 10 strains or lines available

References

• Original: J:291333 Szappanos D, et al., The RNA helicase DDX3X is an essential mediator of innate antimicrobial immunity. PLoS Pathog. 2018 Nov;14(11):e1007397
• All: 1 reference(s)