Gne^em1Smro
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gne^em1Smro
• Name: glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase; endonuclease-mediated mutation 1, Stella Mitrani-Rosenbaum
• MGI ID: MGI:7489807
• Synonyms: Gne^Flag, GneFLAG
• Gene: Gne Location: Chr4:44034075-44084177 bp, - strand Genetic Position: Chr4, 23.1 cM, cytoband B1
• Alliance: Gne^em1Smro page

Mutation origin

• Strain of Origin: CB6F1

Mutation description

• Allele Type: Endonuclease-mediated (Epitope tag, No functional change)
• Mutation: Insertion
• Mutation details: Sequence coding for 3 FLAG epitope was inserted at the last coding exon of the gene, just before the STOP codon. All isoforms of the encoded protein are predicted to include the epitope tag at the C-terminus. (J:336455)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gne Mutation: 47 strains or lines available

References

• Original: J:336455 Ilouz N, et al., In vivo and in vitro genome editing to explore GNE functions. Front Genome Ed. 2022;4:930110
• All: 1 reference(s)