Oprk1^{tm1.1(cre)Rmai}
Targeted Allele Detail

Summary

• Symbol: Oprk1^{tm1.1(cre)Rmai}
• Name: opioid receptor, kappa 1; targeted mutation 1.1, Rajani Maiya
• MGI ID: MGI:7511868
• Synonyms: Oprk1-Cre
• Gene: Oprk1 Location: Chr1:5658689-5676354 bp, + strand Genetic Position: Chr1, 1.89 cM, cytoband A2-A3
• Alliance: Oprk1^{tm1.1(cre)Rmai} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:338351
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Oprk1^{tm1.1(cre)Rmai} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Oprk1 (MGI:97439)

• Mutation details: A floxed neo-P2A-Cre cassette was inserted into the 3' UTR in the last exon 4 of the Oprk1 gene via homologous recombination in the ES cells. The neo-selection cassette was subsequently removed. (J:338351)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Oprk1 (mouse) Summary of all recombinase alleles driven by Oprk1. Alliance mouse Oprk1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Oprk1 Mutation: 30 strains or lines available

References

• Original: J:338351 Paliarin F, et al., A Cre Driver Line for Genetic Targeting of Kappa Opioid Receptor Expressing Cells. eNeuro. 2023 Jul;10(7):ENEURO.0043-23.2023
• All: 1 reference(s)